We are pleased to inform you that the GPS 1.10 will be retired, since new version of GPS 2.0 has been released. Here, we are grateful for your support, feedback and patience for this web site. And we wish our newly updated software of GPS 2.0 will be more helpful for your research. Please keep writing to me if you have any concerns on either GPS 1.10 or GPS 2.0.

The website of GPS 1.10 will be closed in twelve months.

Here, please let us to introduce the newly-released software of GPS 2.0 for you. The GPS 2.0 has been implemented in JAVA, as the first stand-alone software for computational phosphorylation, and could predict kinase-specific phosphorylation sites for 408 human PKs in hierarchy. The GPS 2.0 could be easily installed on your computer or laptop. Finally, the GPS 2.0 is freely available at:


The CUCKOO Workgroup,

Nov. 19, 2007





For publication of results, please cite the following article:

1. Yu Xue, Fengfeng Zhou, Minjie Zhu, Guoliang Chen, and Xuebiao Yao. GPS: a comprehensive www server for phosphorylation sites prediction. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W184-7.

2. Fengfeng Zhou, Yu Xue, Guoliang Chen, and Xuebiao Yao. GPS: a novel group-based phosphorylation predicting and scoring method. Biochem Biophys Res Commun. 2004 Dec 24;325(4):1443-8.

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